Nevasic has been clinically trialled and proven beyond doubt

Thankfully, you don’t need to take our word for it. Some of the world’s leaders in motion sickness research have tested it for you

It is known that approximately 90% of adults will suffer at some point and that children probably suffer the worst symptoms. It is also known that the elderly are also highly susceptible.

Travel sickness can be an everyday occurrence, not something limited to seasonal events like holidays as some would like to have you think. Motion Sickness is an area where the experts can not come together on which drugs to give you, or if in fact the drugs work either partially or completely. One thing is certain – all drugs bring unwanted side effects with them.
The ears (Vestibular Labyrinths) are regarded as “emetic detectors” and play a vital part in the generation and passage of signals to the brain.

The ears together with the brain and gut are the three primary organs involved in the process of emesis.
We have demonstrated that issuing the specifically identified and constructed tones, frequencies and pulses in this programme to the ear in a direct mode we disrupt the normal signal chain at the Vestibular level and therefore affect the chain. By affecting the chain in this manner we have also demonstrated the ability to stop and prevent emesis or sickness.

[h4_heading]What is Motion Sickness?[/h4_heading]

It is researched, proven and documented that our Vestibular System, within our inner ear is what keeps us balanced. Research also reveals that in communicating with the brain the inner ear or “Vestibular Labyrinth” is regarded as an “emetic” detector taking part in the process of “emesis”.

[h4_heading]How?[/h4_heading]

It is believed the “vomiting control centre is within the brain – but its exact location has still not been identified. The stomach clearly is involved.brainstomachear

[h4_heading]Motion sickness clinical trial[/h4_heading]

The MRC Spatial Disorientation Group, Imperial College School of Medicine, London ran a full clinical trial with Nevasic branded as TravelWell.

The trial proved conclusively that the programme is highly effective in combating the symptoms of nausea and vomiting associated with motion sickness.

The report from the trial is lodged with PubMed and available via the National Library of Medicine (USA).

Here is the abstract report: 1: J Travel Med. 2003 Mar-Apr,10(2):108-11 Behavioral methods of alleviating motion sickness: effectiveness of controlled breathing and a music audiotape. Yen Pik Sang FD, Billar JP, Golding JF, Gresty MA. The MRC Spatial Disorientation Group, Imperial College School of Medicine, London, United Kingdom.

BACKGROUND: Behavioral countermeasures for motion sickness would be advantageous because of the side effects of antiemetic drugs, but few alternatives treatments are available. The objective of this study was to compare the effectiveness of controlling breathing and listening to a music audiotape designed to reduce motion sickness symptoms, on increasing tolerance to motion sickness.

METHOD: Twenty-four healthy subjects were exposed to nauseogenic Coriolis stimulation on a rotating turntable under three conditions: whilst focusing on controlling breathing; listening to a music audiotape; or without intervention (control). The three conditions were performed by each subject according to a replicated factorial design at 1-week intervals at the same time of day. Ratings of motion sickness were obtained every 30 seconds. Once a level of mild nausea was reached subjects commenced controlling breathing or listened to the music audiotape. Motion was stopped after the onset of moderate nausea.

RESULTS: Mean (+/- SD) motion exposure time in minutes tolerated before the onset of moderate nausea was significantly longer (p <.01) for controlling breathing (10.7 +/- 5.6 min) and longer (p <.01) for music (10.4 +/- 5.6 min) compared with control (9.2 +/- 5.9 min).

CONCLUSIONS: Both controlling breathing and the music audiotape provided significant protection against motion sickness. They are easy to implement and free of side effects.

Publication Types: Clinical Trial Controlled Clinical Trial

PMID: 12650654 [PubMed – indexed for MEDLINE] Click the below line or copy and paste it to your address bar to view this information direct within the pages of PubMed (United States National Library Of Medicine: http://www.ncbi.nlm.nih.gov

The report was published by the International Society of Travel Medicine (http://www.istm.org/). To obtain the correct report quote “Journal of Travel Medicine Volume: 10 • Issue: 02 • 2003 • March • Page: 108”

More information covering the physical act of being sick or the process of EMESIS.

Courtesy of Medscape / Medline:-

Physiology of chemotherapy-induced emesis and antiemetic therapy.

Predictive models for evaluation of new compounds.
Drugs 1997 Feb;53(2):206-34

(ISSN: 0012-6667)

Veyrat-Follet C; Farinotti R; Palmer JL
Laboratoire GlaxoWellcome, Unite de Biocinetique, Evereux, France.

The physiology of emesis has been studied for several hundred years, focusing on the different centres involved and the mechanics of expulsion. The vomiting centre receives inputs from various emetic detectors such as the gut, the vestibular labyrinths and the chemoreceptor trigger zone. Emesis is a common disabling effect in motion sickness, postoperative conditions and in radio- and chemotherapy. Our current understanding of the mechanisms has been provided mainly by the recent introduction of serotonin 5-HT3 receptor antagonists into therapeutic use. Nevertheless, despite the considerable advances made in the understanding of the different pathways involved in emesis, there are number of areas that still require experimental investigation. Different animal and human models are available to study the physiology of emesis and to evaluate the antiemetic activity of new compounds, but they need to be predictors of clinical situations. Language: English
MEDLINE Indexing Date: 199706
Publication Type: JOURNAL ARTICLE; REVIEW (141 references); REVIEW, TUTORIAL
Unique NLM Identifier: 97180566
Journal Code: M

To see this review go to Medscape then select Medline and enter the following line in the

search by author field.

Veyrat-Follet C; Farinotti R; Palmer JL

[h4_heading]Courtesy of Medscape / Medline :-[/h4_heading]

Maternal susceptibility to nausea and vomiting of pregnancy: is the vestibular system involved?

Am J Obstet Gynecol 2002 May;185(5 Suppl Understanding):S204-9 (ISSN: 0002-9378)

Black FO
Legacy Clinical Research and Technology Center,

Department of Neurotology Research, Portland, OR 97208-3950, USA.

Nausea and vomiting of pregnancy shares many characteristics with motion sickness, a vestibular dependent phenomenon. A number of physiologic changes that occur in normal pregnancy are also known to accompany nausea and vomiting in patients with motion sickness and certain vestibular disorders. This chapter summarizes some shared features of both phenomena. The unmasking of subclinical vestibular disorders may account for some cases of hyperemesis gravidarum. Hormonal effects on neurotransmitter function may also play a role in nausea and vomiting of pregnancy and in some vestibular disorders; however, the specific neural mechanisms of nausea and vomiting have not been identified. Until the neurochemical processes underlying these phenomena are understood, prevention and management will remain in the domain of astute, but so far limited, clinical observation.

Indexing Check Tags: Female; Human; Support, Non-U.S. Gov’t; Support, U.S. Gov’t, Non-P.H.S.; Support, U.S. Gov’t, P.H.S

Language: English

MEDLINE Indexing Date: 200206

Publication Type: Status: Completed

Publication Type: Journal Article

Grant ID: NIDCD 00205

PreMedline Identifier: 0012011887

Unique NLM Identifier: 22005552

Journal Code: AIM; IM; S

To see this review go to Medscape then select Medline, enter the following line in the search by author field. Black FO

[h4_heading]North East Valley Division Of General Practise Victoria – Australia[/h4_heading]

While this authority has not tested our product there is strong synergy in how we both feel the processes of Emesis actually work. This is demonstrated in the following page – the contents of which we do not display as a respect for their copyright.

http://www.nevdgp.org.au/ginf2/murtagh/general/Travelsickness.htm

(This link opens in a new window – it is not a popup)

About the writer:

JOHN MURTAGH … Patient Information Sheets. .. 1st Edition

Professor John Murtagh is executive director of education of the RACGP and adjunct professor in the department of community medicine and general practice at Monash University.
… Provided by the Courtesy of Servier

Copyright John Murtagh, Patient Education, McGraw-Hill Book Company, Jam Software Pty. Ltd. – Click copyright link for further information.

[h4_heading]Your LOCAL Pharmacy[/h4_heading]

Your local pharmacists in the UK will be able to offer advice on a variety of products and they have been supplied information covering our products as we featured in Pharmacy Magazine and Pharmacy Products Review in June and July 2001.

They can also offer leaflets on the subject of Vomiting. The following leaflet can be obtained at a pharmacy displaying Unichem Community Pharmacy information.

Sickness – Upset Stomach Information Leaflet.

Common Causes of Vomiting:

The most common reason for vomiting is reflex vomiting due to conditions such as stomach inflammation (gastritis), stomach ulcer and a narrowing at the stomach’s exit, called pyloric stenosis. Other conditions that produce vomiting include appendicitis, bowel obstruction and pain from kidney or gallstones. Certain drugs such as aspirin or ibuprofen may also cause stomach irritation and vomiting in susceptible people. Motion sickness and Ménière’s Syndrome – which affects a part of the ear known as the vestibular part – are two other well known causes of sickness and vomiting. Vomiting can also be a feature of many serious illnesses including various brain lesions caused by infection or swelling. It is also common symptom of migraine and is also associated with psychological conditions such as hysteria, anxiety and nervous tension.